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BK polyomavirus-associated haemorrhagic cystitis (BKPyV-HC) is rare in haematology patients other than those undergoing allogeneic HSCT. When it does occur, it is in 8%-25% of paediatric and 7%-54% of adult recipients undergoing allogeneic HSCT. Haemorrhagic cystitis contributes to post-HSCT morbidity by prolonging hospital stay and severely worsening the quality of life. The European Leukaemia Network, the Infectious Diseases Working Party of the European Association for Blood and Marrow Transplantation (IDWP-EBMT), the Infectious Disease Group of European Organization for Research and Treatment of Cancer, and the Immunocompromised Host Society (ICHS) joint initiative have just published the latest guidelines for management of BK polyomavirus-associated haemorrhagic cystitis.